Anti-Thrombin (human)

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Anti-Thrombin (human)
368,00 $US

Availability: In stock

Anti-Thrombin (human)
Description

Details

Cat. No.

 HYB 109-03

 Product name

 Anti-Thrombin (human)

 Description

 Mouse monoclonal antibody

 Specificity

 HYB 109-03 binds to human thrombin and to complex of human thrombin with the thrombin inhibitor hirudin. No cross-reaction is seen with prothrombin. 

 Immunogen

 Thrombin isolated from activated human plasma 

 Application

 ELISA, WB

 Species reactivity (positive)

 Human

 Species reactivity (negative)

 Not determined

 Subclass

  IgG1/k

Gene ID

 2147

Clone number

 5D10

Epitope

Not determined

Content

 Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.

Purification

 Protein-A purified

Form

Liquid

Solvent

 0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide

Storage

 4-8ºC without exposure to light. No precautions necessary during handling.

Target

 Thrombin is the active enzyme that splits fibrinogen into fibrin in final stage of blood coagulation. It is generated from its circulating inactive precursor, prothrombin, by the action of factor Xa aided by factor Va, phospholipid and calcium ions. Thrombin is a glycoprotein formed by a 6-kDa A chain linked by a disulfide bridge to a 31-kDa B chain which carries the serine protease catalytic site.
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