Anti-α1-antitrypsin (human, α1-AT, native and denatured)

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Anti-α1-antitrypsin (human, α1-AT, native and denatured)
368,00 $US

Availability: In stock

Anti-α1-antitrypsin (human, α1-AT, native and denatured)
Description

Details

Cat. No.

 HYB 191-01

 Product name

 Anti-α1-antitrypsin (human, α1-AT, native and denatured)

 Description

 Mouse monoclonal antibody

 Specificity

 HYB 191-01 is specific for human α1-AT (native and denatured).

 Immunogen

 α1- AT isolated from human plasma

 Application

 ELISA, WB

 Species reactivity (positive)

 Human

 Species reactivity (negative)

 Not determined

 Subclass

  IgG1/k

Gene ID

 5265

Clone number

 3B7

Epitope

Not determined

Content

 Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.

Purification

 Protein-A purified

Form

Liquid

Solvent

 0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide

Storage

 4-8ºC without exposure to light. No precautions necessary during handling.

Target

 The serum glycoprotein α1-antitrypsin also called α1-AT, is a typical member of the serpin family (serine protease inhibitors), and, an inhibitor of trypsin. α1-AT is synthesized in the liver thus as a single polypeptide chain of approximately 51 kDa showing a marked degree of genetic polymorphism due to the presence of over 20 different alleles. Individuals homozygous for α1-AT deficiency are predisposed to pulmonary emphysema and hepatic cirrhosis.
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