Anti-NGAL (human, monkey)
Mouse monoclonal antibody
HYB 211-01 is specific for human NGAL (neutrophil gelatinase-associated lipocalin).
Human recombinant NGAL in monomer and dimer forms
ELISA, WB, IHC
Species reactivity (positive)
Human, shows some cross-reactivity with NGAL from Cynomolgus monkey (Macaca fascicularis).
Species reactivity (negative)
Differs from those of HYB 211-01, ABS 038-14, -15 and ABS 062-33.
Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
4-8ºC without exposure to light. No precautions necessary during handling.
Neutrophil gelatinase-associated lipocalin (NGAL; also called lipocalin 2, siderocalin and neutrophil lipocalin) is a member of the lipocalin family of proteins which bind and transport small lipophilic molecules. NGAL is released by activated neutrophils and occurs as 25-kDa glycosylated single protein chain monomers, which form dimers and small amounts of higher oligomers, as well as complexes with matrix metalloproteinase 9 (MMP-9; gelatinase B). Low level expression of NGAL in a variety of epithelia may be increased in inflammation or cancers. Expression of NGAL in the kidney is dramatically increased by acute kidney injury.